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Amgen Senior Manager Health Economics Modelling in Uxbridge, United Kingdom

Senior Manager Health Economic Modelling

Amgen Global Health Economic Modelling team is looking for an experienced Senior Economic Modelling Manager who will be responsible designing and executing of economic modelling activities from early development to evidence generation within a product life cycle.

This is a great opportunity to become a subject matter expert within Economic Modelling whilst collaborating and driving business decisions for Amgen.

If you are looking for your next career step within Economic Modelling and want to be part of our mission – To serve patients – which drives all that we do, apply or get in touch.

Our Global Economic Modelling team:

Our Global Economic Modelling Center of Excellence (COE) is based in Rotkreuz, Switzerland, Uxbridge, UK, and Thousand Oaks, USA. We work in international cross-functional teams developing and supporting product value strategy focusing on evidence-based economic modelling throughout the product life-cycle. The activities of the Global Economic Modelling COE include early modelling for strategic input to development, design and pricing, core models and local model adaptations for Health Technology Assessment (HTA) and price and reimbursement submissions, as well as tools supporting field-based key account value communication.

Senior Manager Economic Modelling role overview:

As a Senior Manager, you will be the Economic Modelling COE product lead for selected Amgen products in the area cardiology/bone/metabolic disease. The successful candidate will be responsible for designing and executing the economic modelling activities involved in the global launch of new products/indications and in the products life cycle management. In particular, the successful candidate will lead the development of the core and the local adaptations of cost-effectiveness and budget impact models in collaboration with cross-functional local and global teams.


  • Lead core cost-effectiveness and budget impact model development.

  • Lead local model adaptations to address local requirements, being responsible for the project management, content and execution.

  • Manage a team of junior economic modellers.

  • Effective communication to HTA and reimbursement authorities

  • Interpretation of clinical studies results.

  • Plan and perform additional statistical analyses needed for local adaptations.

  • Input into the design and interpretation of global/local evidence generation activities/studies.

  • Critically review and select relevant model inputs.

  • Generate base case and sensitivity/scenario results.

  • Discuss, re-analyze and present model results.

  • Report the economic section of HTA pricing and reimbursement submissions.

Basic Qualifications and preferred experience:

  • Master’s degree or equivalent in Health Economics or in a quantitative field such as statistics, epidemiology or engineering; strong preference for PhD qualification

  • Broad and proven experience in life sciences or pharmaceutical industry, academia or reimbursement agencies

  • Strong experience in development of core and local adaptation of cost-effectiveness, budget impact models

  • Strong statistical skills, particularly in biostatistics and epidemiology

  • Strong excel programming skills and analytical skills

  • Excellent communication and project management skills

  • Previous line management experience

  • Experience using Visual Basic, TreeAge Pro, R, SAS, STATA, WinBUGS and other software for statistical analyses.

  • Previous experience in osteoporosis and/or cardiovascular disease

Location: Uxbridge, UK or Rotkreuz, Switzerland

Remuneration: Competitive salary & comprehensive benefits package including bonus scheme

The company:

Amgen is one of the world’s largest independent biotechnology companies, with global revenue in excess of $20 billion and over 20,000 employees globally. For more than 35 years, Amgen has pioneered biotechnology breakthroughs, to bring state-of-the-art medicines from laboratory to the patient. Amgen has not only discovered and developed innovative human therapeutics, but has invested in cutting edge manufacturing capability and support services to deliver these exciting therapies to medical teams around the world.

We understand that to successfully sustain and grow as a global enterprise and deliver for patients — we must ensure a diverse and inclusive work environment.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.