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Amgen Vice President, Global Oncology Early Development in Thousand Oaks, California


At Amgen, every challenge is an opportunity. And every opportunity brings the potential to change lives. Our shared mission—to serve patients—has driven our status as one of the world’s preeminent biotechnology companies, reaching over 10 million patients worldwide. Leverage your high-level expertise to lead and forge partnerships that advance the biotechnical and biopharmaceutical science that can turn the tide of serious, life-interrupting illnesses.

Vice President of Global Oncology, Early Development


What you will do

Amgen Oncology: for every patient, a solution. We aim to deliver new therapies to patients with the greatest unmet need, and our team is advancing the largest Oncology pipeline in Amgen history. Utilizing our innovative technology platforms – Bispecific T Cell Engagers (BiTE®s), Complex Biologics, Small Molecules, and Antibody Drug Conjugates – we are addressing cancer broadly through novel target discovery and therapeutic approaches. We are seeking an experienced, ambitious and collaborative clinical and scientific leader to advance these molecules to their fullest potential for patients.

In this vital role, you will lead Amgen’s industry leading BiTE® and BiTE® enabler early development portfolio and organization. You will be responsible for advancing our early pipeline clinical strategy through early clinical development, and you will identify and champion complementary external programs through active participation in business development opportunities.

Additionally, you will be part of the cross-functional Oncology leadership team, partnering with Discovery Research to share clinical considerations for drug discovery and to pave the strategy across target identification, candidate optimization, and clinical development plans. You will lead a team of experienced drug development professionals and will be responsible for building a fit-for-purpose group that fosters diversity of thought and individual backgrounds while prioritizing staff engagement and development activities for the business.


  • Oversee early development BiTE® and BiTE® enabler early development portfolio, defining the vision, strategy and long-term lifecycle plan, and mobilizing the team to execute against it

  • Work together with Research leadership counterparts on key portfolio progression decision that span from target identification to early phase clinical trial development

  • Collaborative approach across functions within R&D and Commercial to drive clinical development programs forward from early to late stage

  • Serve as a senior advisor or executive sponsor for functional, cross-functional and/or corporate initiatives

  • Source and evaluate business development opportunities

  • Establish and nurture strategic partnerships including public-private and private-private

  • Co-Chair of Early Portfolio Review Meeting (EPRM) and Early Development Review Committee (EDRC) for the Oncology TA, fostering cross-functional collaboration and technical advice to advance novel programs into the clinic

  • Create and maintain highly motivated development teams through leadership, people management and mentorship with a focus on career development

  • Ensure effective performance management of direct reports through comprehensive goal setting, regular performance reviews, as well as direct and timely feedback

  • Foster a culture that attracts and retains the best talent

  • Support staff within diversity, inclusion and belonging

  • Proven ability to lead, manage, and motivate others in a complex, multi-functional matrix environment

  • Ability to effectively present ideas and document complex scientific/medical/clinical concepts in both written and oral communication

  • Demonstrated ability to organize and lead expert Clinical Research Advisory Panels

  • History of solving problems while exhibiting superior judgment and a balanced, realistic understanding of issues

  • Superior analytical and problem solving

  • Influence and negotiation skills

  • Management of budget, processes, and people

  • Coaching and mentoring and developing scientific talent

  • Learning agility, flexibility, creativity, and innovation based on program constraints


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Vice President we seek is an experienced leader with the following qualifications.

Basic Qualifications

  • MD or DO degree from an accredited medical school AND

  • Five years of industry or academic research AND

  • 8 years of direct managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources.

Preferred Qualifications

  • Ph.D.

  • Ten (10) or more years of clinical research experience and/or basic science research combined with clinical teaching and patient care activities

  • In-depth understanding of the scientific method and clinical applications based on medical, scientific and practical rationale including knowledge of cancer biology & immunology, pharmacokinetics, biomarker methods, and clinical imaging endpoints

  • In-depth understanding of and proven success in how to conceptualize, design, and conduct complex, global early phase clinical trials

  • Clinical experience in either an accredited academic setting or private practice (including hospital based) setting

  • Industry experience with health authority (HA) interactions and leading phase 1 trials, portfolio-level exposure preferred

  • Understanding of new drug commercialization and business practices

  • Highly skilled in leveraging diverse thoughts and perspectives in clinical strategy development

  • Previous experience in conducting translational and/or clinical research for both small molecules and large molecules

  • Experience with novel clinical trial designs (e.g., Bayesian)

  • Record of high-quality peer-reviewed publications

  • History of solving problems while exhibiting judgment and a balanced, realistic understanding of issues including the ability to anticipate problems and find creative solutions

  • Understanding of regulatory agency organization, guidelines, and practices and ability to negotiate with these groups

  • Knowledgeable in current and possible future, trends, technology, policies, practices and information of the competitive landscape of oncology development

  • Knowledge of Good Clinical Practices (GCP), FDA regulations and guidelines, and applicable international regulatory requirements

  • Strong budget management principles and ability to make financially driven trade-offs

  • Passionate about developing staff and committed to actively bringing in diverse staff and ensuring their perspectives are included in work culture

They will also embody the Amgen leadership attributes which are:

  • Inspire : Create a connected, inclusive, and inspiring work environment that empowers talent to thrive

  • Accelerate : Enable speed that matches the urgency of patient needs by encouraging progress over perfection

  • Integrate : Connect the dots to amplify the collective power of Amgen to drive results for patients, staff, and shareholders

  • Adapt : Lead through change by adapting to an ever-changing environment and defining a clear course of action to deliver results


What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

The annual base salary range for this opportunity in the U.S. is $307,500 - $512,500.

In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Amgen’s Commitment to Our Staff

At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our “people-first” philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business.

We equip all our staff members to live well-rounded, healthy lives. Most recently, Amgen added benefits for transgender employees and continues to pride itself on industry-leading, family-friendly offerings for families of all compositions.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.