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Amgen Sr. Scientist - Confocal Microscopy in Thousand Oaks, California


You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Sr. Scientist - Confocal Microscopy


What you will do

Let’s do this. Let’s change the world. In this vital role you will perform fluorescence microscopy imaging studies using confocal microscopy to characterize sub-cellular localizations of proteins or organelles. You will join our Induced Proximity Platform (IPP) team, which specializes in the emerging proximity-based drug discovery programs for Oncology, Cardiometabolic, and Inflammation targets. We seek to understand these newer waves of proximity-inducing drugs and characterize their mechanisms of action at a sub-cellular level.

The successful candidate will join our highly enthusiastic team of scientists to develop and characterize visualization tools and use appropriate microscopy to understand the mode of action of our proximity-inducing molecules. A consistent track record of working and publishing high-quality imaging-based science in a related field and have in-depth expertise in confocal microscopy skills is required.


  • Routinely culture and prepare mammalian cell line samples as needed for imaging

  • Prepare and optimize fluorescence reagents and specimens for imaging

  • Use confocal microscopy to collect still or time-lapse images using fixed or live specimens

  • Perform image analysis and quantitation using software such as ImageJ, CellProfiler, Photoshop

  • Manage and maintain imaging instruments as needed

  • Provide guidance and support for various imaging projects within the IPP team

  • Keep clear records of experimental details, raw and processed data

  • Present research findings to IPP leadership and other cross-functional teams on time


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Sr. Scientist with these qualifications.

Basic Qualifications:

Doctorate degree or

Master’s degree & 3 years of directly related research experience or

Bachelor’s degree & 5years of directly related research experience and

Advanced and proficient understanding and use of technical principles, theories, and concepts to perform an expansive range of work in a role and

Basic knowledge of related and adjacent disciplinary areas.

Preferred Qualifications:

  • Experience with designing and developing appropriate imaging reagents to assess subcellular phenomena using exceptional quality images and movies

  • Experience with point scanning and spinning disk confocal microscopy and deconvolution techniques

  • Demonstrated ability to perform image analysis and familiarity with ImageJ, CellProfiler, Photoshop

  • Experience with IncuCyte and other High Content Imaging instruments

  • Mammalian cell culture and immunofluorescence experience

  • Ability to work in teams collaboratively to develop and optimize appropriate imaging tools set up experiments, and acquire images

  • A highly independent and self-driven scientist who can drive complete discovery efforts on time with minimal everyday guidance


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.