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Amgen Sr Scientist (Cardiometabolic Disorders) in Thousand Oaks, California

  • Job Description HOW MIGHT YOU DEFY IMAGINATION? You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role. Sr Scientist, Cardiometabolic Disorders


What you will do Let’s do this. Let’s change the world. We are building upon our solid Cardiovascular foundation and long-term dedication to patients by developing a whole new class of novel molecules – and we need top talent to ensure these molecules become medicines and realize their potential for helping patients.The Sr Scientist will be a member of the Department of Cardiometabolic Disorders within Amgen Research located in Thousand Oaks, CA. The position will include conceptualizing and proposing therapeutic target programs with a sound and compelling scientific rationale and conducting in vivo and in vitro preclinical Cardiometabolic disease studies with a focus on PAH, vascular disease and/or heart failure and their use in the pharmacological assessment of drug candidates.In addition, the Sr Scientist will be encouraged to demonstrate critical thinking, exhibit excellent communication skills and prosecute programs with a high degree of integrity. They will be involved in the identification and validation of potential targets based on their knowledge of Cardiovascular and metabolic disease. The successful candidate will also support existing drug programs and provide excellent in vivo data by directly generating data themselves and with assistance from associates.


What we expect of you We are all different, yet we all use our outstanding contributions to serve patients. Responsibilities include:

  • Critical and original thinking and drive to deliver innovative medicines for patients

  • Study design, data collection, analysis, and interpretation in preclinical models of Cardiometabolic disease

  • Excellent communication and interpersonal skills that enable effective team interactions and communication of key data to all key stakeholders in a succinct, balanced and compelling manner.

  • The candidate must demonstrate or quickly develop a strong capability of operating in a matrix work environment seeking input and support from other stakeholders and show appropriate use of resources. The ability to collaborate cross-functionally is critical.

  • Exceptional in vivo technical skills, capable of generating highly reproducible data of outstanding quality

  • Careful and precise data documentation, keeping accurate records of raw data and analysis in electronic databases for IP and data integrity purposes

  • Basic knowledge of statistical methods applied in a consistent and rigorous manner to all data sets generated.

  • Draft manuscripts, posters and presentations for external peer-review publication and conference attendance

  • Produce reports and/or presentations of study plans and results

  • Remaining aware of historical and current research in cardiometabolic disease and the clinical findings of therapeutic agents in clinical development Basic Qualifications Doctorate degreeORMaster’s degree and 4 years of scientific experienceORBachelor's degree and 6 years of scientific experience Preferred Qualifications

  • PhD and 3+ years postdoc experience

  • Industry experience preferred but not required

  • Direct hands-on experience with in vivo preclinical models of cardiovascular disease

  • Sound knowledge of integrated physiology, with proven experience in the field of hormonal and cellular control of cardiovascular risk factors

Knowledge of genomic analysis is a plus

Written and oral presentation of their research in the form of impactful research papers, conference posters and oral presentations


Some of the vast rewards of working here As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

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If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States, Puerto Rico and Canada to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.