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Amgen Sr. Associate Scientist - Next Gen Sequencing in Thousand Oaks, California


You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Sr. Associate Scientist, Next Generation Sequencing


What you will do

Let’s do this. Let’s change the world. In this vital role you will be responsible for wet lab NGS experiments to advance programs in the large molecule portfolio and to support display-based protein engineering campaigns. Additionally, as a Sr. Associate Scientist , you will contribute to the development of innovative NGS workflows to support a high-throughput, automated synthetic biology pipeline in Therapeutic Discovery.

Biologics Optimization is seeking a highly motivated Sr. Associate Scientist to join our team in Thousand Oaks, CA. We are a multidisciplinary group in Research with capabilities in protein engineering, cloning, expression, purification, and analysis of therapeutic proteins. Biologics Optimization is responsible for the engineering, production, assessment, and final selection of large molecule drug candidates that advance to Process Development.

  • Develop and optimize NGS sequencing and library preparation workflows, primarily for short-read sequencing on Illumina instruments (e.g., MiSeq)

  • Make NGS libraries; run and maintain sequencers

  • Communicate with partner groups to coordinate and track NGS sequencing requests

  • Design and implement high throughput workflows using automated equipment

  • Provide scientific results that support the generation of publications, patents, or regulatory submissions, and participate in internal and external scientific meetings.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients.

The scientific professional we seek is a leader with these qualifications.

Basic Qualifications:

Master’s degree and 3 years of experience


Bachelor’s degree and 5 years of experience

  • Demonstrated expertise in molecular biology and Next-Generation Sequencing (NGS) technology

  • Hands-on experience in NGS library construction

  • The ability to independently troubleshoot experiments and build new assays and workflows

Preferred Qualifications:

  • Hands-on experience in library construction of Amplicon-Seq and/or operation of Illumina NGS instruments

  • Experience in processing and handling large data sets; Linux and/or scripting or coding skills a major plus

  • Familiarity with automated liquid handlers such as Tecan or LabCyte Echo systems

  • Experience with display technologies for protein engineering


Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.