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Amgen Senior Scientist - Clinical Pharmacology, Modeling and Simulation in Thousand Oaks, California


You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Senior Scientist - Clinical Pharmacology, Modeling and Simulation


What you will do

Let’s do this. Let’s change the world. The Amgen Clinical Pharmacology Modeling and Simulation (CPMS) team is seeking a Senior Scientist who will be based at our Thousand Oaks, CA corporate offices. As part of the Clinical Pharmacology, Modeling and Simulation department, the Modeling and Simulation Senior Scientist will support Amgen clinical development and translational sciences programs across multiple therapeutic areas. In this vital role you will:

  • Building pharmacostatistical models to support Population Pharmacokinetics/Pharmacodynamic (PKPD) and exposure-response analyses using relevant state of the art modeling and simulation techniques.

  • Training in binary and categorical data analyses, time-to-event (hazard) models, Poisson models, MCMC and Bayesian methods as applied to exposure-response analyses and Population PK and PKPD analysis.

  • Performing meta-analysis using proprietary and/or literature data.

  • Participating in cross-functional project teams and providing scientific input for dose selection, early and late study designs using modeling and simulation inputs.

  • Contributing to clinical pharmacology strategy for the programs and implementing project plans.

  • Generating modeling reports and supply to the summary documents for regulatory submissions.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The [vital attribute] professional we seek is a [type of person] with these qualifications.

Basic Qualifications:

Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]


Master’s degree and 3 years of Pharmacokinetics/Pharmacodynamic or statistical modeling experience


Bachelor’s degree and 5 years of Pharmacokinetics/Pharmacodynamic or statistical modeling experience

Preferred Qualifications:

  • PhD in pharmacometrics, pharmaceutical sciences, applied statistics/mathematics, biostatistics, and/or engineering or related fields with equivalent professional degrees (e. g. MD, PharmD) with 3 years of PK/PD or statistical modeling experience.

  • 2+ years industry or relevant academic experience in pharmacometric analyses and/or applied biostatistics of small molecules and/or biologics.


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.