Amgen Senior Associate Scientist - Medicinal Chemistry in Thousand Oaks, California
Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in Thousand Oaks, CA (ATO).
This Senior Associate Scientist role will be part of an innovative Medicinal Chemistry group with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development, including opportunity to work within Amgen’s Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. The Senior Associate Scientist will work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry teams, including troubleshooting of synthetic routes and reactions, scouting of new synthetic routes and performing high difficulty synthetic chemistry. Furthermore, he/she will contribute to the design of new compounds and the development of structure-activity relationships. This individual will perform structural determinations using NMR and mass spectral techniques and purify compounds using a variety of techniques. They will be recognized as a lab leader and should demonstrate excellent verbal and written communication skills. Additional responsibilities include maintaining laboratory notebooks, participating in group and project meetings and, as needed, presenting to groups and aiding in the writing of papers and patent applications.
Master’s degree and 3 years of laboratory experience
Bachelor’s degree and 5 years of laboratory experience
Doctorate degree in chemistry specializing in organic synthesis by Oct 2020 OR 6+ years of focus or specialization in synthetic organic or medicinal chemistry (academic and/or industrial)
Track record of accomplishments (e.g., peer-reviewed publications)
Demonstrated ability to scout and troubleshoot synthetic routes, and perform high difficulty synthetic chemistry
Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods
Demonstration of good lab practices, with particular attention to safety
Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams
Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world’s leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.
Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live-cell therapies.
If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.
Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.