Amgen Process Development Senior Associate - Pivotal Drug Substance Technologies (DST) in Thousand Oaks, California
Amgen is seeking a Process Development Senior Associate to join the Pivotal Drug Substance Technologies (DST) organization in Thousand Oaks, CA. The pivotal DST organization is responsible for developing cell culture and purification manufacturing processes for Amgen’s late stage pipeline.
Scope of work includes developing cell culture and purification processes for recombinant proteins to improve the production yields, evaluating process robustness through process characterization, transferring processes to manufacturing, and conducting other relevant experiments such as for facility fit and raw material evaluation.
Work in a team environment to contribute to drug substance process development.
Execute mammalian cell culture experiments at different scales in shake flasks and bioreactors.
Execute purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed.
Document experimental data in lab notebooks.
Analyze the data and present to the team.
Author technical reports and support regulatory filing as needed.
Contribute to technology development projects to seek continuous improvement in reliability and efficiency.
The candidate will have opportunities to work in cell culture development and purification development to become a well-rounded process development scientist with experience in upstream and downstream.
Bachelor’s degree and 2 years of Scientific or Operations experience
Degree in Chemical Engineering, Biochemistry, Biotechnology, Bioengineering, Biomedical engineering, or Bioprocessing discipline or relevant experience in the pharmaceutical or related industry preferred.
Relevant hands-on lab experience in cell culture or protein purification.
Attention to details and critical thinking ability.
Experience in Design of Experiments and statistical analysis is a plus.
Strong oral and written communication skills.
Ambitious and strong organization skills.
Strong interpersonal skills, and the ability to work in a dynamic and collaborative environment.
We understand that to optimally sustain and grow as a global enterprise and deliver for patients - we must ensure a diverse and inclusive work environment.
Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.
Amgen focuses on areas of high unmet medical need and demonstrates its expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world’s leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.
If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.
Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.