Amgen Process Development Scientist - Pivotal Bioprocesses Sciences & Technologies in Thousand Oaks, California
HOW MIGHT YOU DEFY IMAGINATION?
You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.
Process Development Scientist - Pivotal Bioprocesses Sciences & Technologies
What you will do
Let’s do this. Let’s change the world. In this vital role you will be responsible for development, characterization, scale-up and support of drug substance processes to enable commercial advancement of programs from Ph II/III clinical trials to marketing application.
Work in a coordinated group in which cell culture and purification scientists work together to advance Amgen’s rich, exciting and dynamic pipeline. With Amgen’s biology first approach, the position provides the outstanding opportunity of being able to work on multiple modalities from antibodies and oncolytic viruses to bispecifics and siRNAs.
The Pivotal Drug Substance Process Development organization at Amgen develops, characterizes and supports the commercialization of biologics drug substance manufacturing processes for all late-stage programs across the Amgen portfolio.
Apply established platform approaches and problem-solving skills to rapidly tackle drug substance challenges and build robust processes with efficient experimentation
Drive innovation and utilize out-of-the-box thinking to contribute to technology development
Expand and develop skills in cell culture and purification, thereby further contributing to the integrated group
Participate in drug substance teams and collaborate cross functionally with analytical and drug product representatives to deliver drug substance manufacturing processes in a phase appropriate manner.
Deliver process amenable to cGMP operation and carry out results of drug substance in a cGMP manufacturing environment
Author, or provide direction for the authorship of, technical report or CMC regulatory submissions which may require minimal additional editing
What we expect of you
We are all different, yet we all use our outstanding contributions to serve patients. The collaborative professional we seek is a dynamic thought leader with these qualifications.
Master’s degree & 4 years of cell biology, molecular biology, immunology or biochemistry experience
Bachelor’s degree & 6 years of cell biology, molecular biology, immunology or biochemistry experience
Doctorate in Chemical Engineering, Biochemical Engineering, or other relevant sciences
Consistent track record of decision-making and trouble-shooting protein drug substance purification processes, preferably in a process development environment
Strong understanding and extensive hands-on experience in protein chromatography, including affinity, ion exchange, and hydrophobic interaction chromatography
Experience in filtration operations, including ultrafiltration/diafiltration
Understanding of protein characteristics and critical attributes to direct product/process control strategies
Proven ability to independently identify, develop and implement scientific solutions to practical problems.
Motivated self-starter with excellent interpersonal and organizational skills
Leadership experience of progressively increased scope and ability to encourage and lead a group of scientists
community through a sustained record of peer reviewed publications
Demonstrated success working with diverse team members in a dynamic, cross-functional environment
Familiarity with design of experiments and statistical analysis of data
Knowledge of license application and the drug development process
Exposure to cGMP manufacturing and CMC components of regulatory submissions
Some of the vast rewards of working here
As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.
Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey
A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
Equal Opportunity Statement
If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.
Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.