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Amgen Pilot Plant - Senior Associate (Downstream) in Thousand Oaks, California


You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.


What you will do

Senior Associate Pilot Plant

Live - What you will do

Let’s do this. Let’s change the world. In this dynamic role you will execute a variety of production and technology related operations in the Downstream (Purification) area of their large-scale pilot plant. The pilot plant delivers data and material to support process development of early and late stage clinical biologic molecules. The plant also prototypes and develops new technologies to support advancement of Amgen’s equipment and operations for current and future biologic facilities. Responsibilities include:

  • Completing a variety of production-related operations in a large-scale facility, including but not limited to: performing processing on the floor (purification of Drug Substance)

  • Perform supporting activities such as buffer preparation, and equipment set-up/cleaning, and completion of downstream operations.

  • Completing production runs, experiments, commercial program support, and characterization efforts.

  • Performing ‘hands-on’ work in the plant.

  • Defining & documenting operation practices, ensuring documentation accurately reflects operations performed, developing, and implementing area improvements (efficiency and safety) applying lean principles, commissioning equipment, and participating in operations meetings.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Manufacturing professional we seek is a collaborative partner with these qualifications.

Basic Qualifications:

Master's Degree


Bachelor's Degree & 2 years of Manufacturing, Scientific or Operations experience


Associate's degree & 6 years of Manufacturing, Scientific or Operations experience


High school diploma/GED & 8 years of Manufacturing, Scientific or Operations experience

Preferred Qualifications:

  • Bachelor’s degree in Biology, Chemistry, Biochemical/Chemical Engineering, or other relevant field

  • 3+ years of experience in process development, biotechnology manufacturing, or Life Sciences or Engineering fields

  • Solid knowledge of upstream/downstream operations

  • General knowledge of the associated analytical and media/buffer preparation techniques

  • Energetic and technically-minded individuals, with strong interpersonal, leadership, and organizational skills

  • Demonstrated ability to learn new systems and applications, and various downstream techniques

  • Demonstrated ability to work effectively in team and/or project environments


Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.