Amgen Global Health Economics Senior Manager in Thousand Oaks, California

The Health Economics Senior Manager develops and leads a Global Health Economics (GHE) value-evidence strategy for either an Amgen pipeline asset or Marketed Product.

Responsibilities include:

  1. Integrates with a global research team and program to support the asset, as well as with individual regional and local business units, in alignment with the strategy, tracks and executes the GHE plan and delivers against goals.

  2. Coordinates product and project activities.

  3. Has budget responsibility and may immediately, or over time direct and develop staff.

  4. Develops strategy and selection of Patient Reported Outcomes (PROs) for interventional trials and observational studies. Develops FDA briefing documents for PRO label discussions.

  5. Develops core economic models with vendors or Amgen internal center of excellence. Works with Amgen international affiliates to adapt core economic models for regional use

  6. Designs existing data studies, develops or approves research project plans, and oversees execution.

  7. Develops and communicates the Global Value Dossier (GVD) and final value propositions and validates that the regional dossiers (e.g. AMCP Dossier) are consistent with the GVD.

  8. Assists in the development, creation, and review of the US AMCP Dossier for relevant pipeline assets

  9. Designs or approves GHE-related aspects such as statistical analysis plan (SAP) of observational studies and interventional trials and consults on study execution.

  10. Develops and oversees/conducts relevant meta-analysis, PRO, systematic review, utility measurement or other outcomes research study as determined by product evidence generation plans/strategy

  11. Helps design product evidence generation strategy and communicate plans to cross functions teams

  12. Serves as the GHE representative for the Global Publication Team and coordinates with affiliates and Regional HE on publication plan

  13. Prepares GHE publications for dissemination.

  14. Develops or consults on global reimbursement strategy and value proposition for payers.

  15. Selects and works with study vendors.

Basic Qualifications:

Doctorate Degree and 2 years of health economics and outcomes research experience


Master's Degree and 6 years of health economics and outcomes research experience


Bachelor's Degree and 8 years of health economics and outcomes research experience

Preferred Qualifications:

Masters or PhD in Health Economics, Outcomes Research, Health Services Research, Pharmacy Administration or related discipline, or PharmD with a post-doctoral fellowship in one of these areas

3+ years' experience in global outcomes research including dossier submissions for reimbursement.

3+ years' experience in PRO/HRQOL research including questionnaire design, evaluation, and/or analysis.

3+ years' experience developing pharmacoeconomic models.

Experience working with consumers of outcomes information

Knowledge of epidemiology, economics, psychometrics and medical writing

Amgen provides a collaborative and creative culture in a company with a strong track record of innovation. Our culture encourages open dialogue and diverse views to land on the best solutions, and we help ensure our staff are equipped to excel today and tomorrow.

Amgen is committed to unlocking the potential for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Global Health Economics contributes by ensuring patient and payer perspectives are incorporated into the value generated for these innovative biologics. The department is committed to developing comprehensive evidence packages across cost modeling, database analysis, and patient reported outcomes to achieve unparalleled health technology submissions.


Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.