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Amgen Computational Chemist in Thousand Oaks, California


You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Computational Chemist


What you will do

Let’s do this. Let’s change the world. Job Description

Amgen is seeking a talented and highly motivated computational chemist to join the computational and data sciences team. In this vital role you will apply computational chemistry and machine learning techniques to help drive drug discovery programs. The primary responsibilities are:

  • Developing and applying cutting-edge machine learning and computational chemistry methods for ligand discovery and optimization.

  • Utilizing structure-based and ligand-based drug design and predictive modeling to advance drug discovery projects.

  • Working closely with an interdisciplinary team consisted of medicinal chemists, protein chemists, structural biologists, and therapeutic biologists, formulating testable hypotheses, designing experiments, and providing thorough analysis to help the next round of design.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a computational chemist with these qualifications.

Basic Qualifications:

Doctorate degree


Master’s degree and 4 years of industry experience


Bachelor’s degree and 6 years of industry experience

Preferred Qualifications:

  • PhD. in Computational Chemistry or related fields with focus in machine learning method development and/or applications.

  • Strong track record of research accomplishment exemplified by three or more first author scientific publications or conference presentations

  • Expertise in building/deploying machine learning models and result interpretation

  • Fluent in Python scripting and/or C++ programing language. Must be familiar with machine learning libraries such as TensorFlow, PyTorch, etc.

  • Working knowledge of contemporary computational chemistry techniques.

  • Experience with one or more molecular modeling suites (MOE, Discovery Studio, Schrodinger, etc.)

  • Strong communication skills and enthusiasm for working in an interdisciplinary team environment


Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.​