Amgen Associate Scientist- Automation, Pivotal Drug Product Technologies in Thousand Oaks, California
HOW MIGHT YOU DEFY IMAGINATION?
You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.
Associate Scientist- Automation, Pivotal Drug Product Technologies
What will you do
Let’s do this. Let’s change the world.
Responsibilities include, but are not limited to, the following:
Independently design and implement experiments to characterize and enable the implementation of new technologies that advance innovative automation, high throughput screening, filling, and analytical capabilities.
Independently design and implement studies to characterize drug product formulations and processes to deliver robust products
Conduct studies to measure drug product stability under various stresses, e.g. formulation screening under accelerated or forced degradation conditions, UF/DF, filtration, and freeze/thaw, for products in various formulations and formats (liquid, lyophilized, vials, pre-filled syringes, etc.)
Evaluate product attributes through analytical testing, e.g. measurement of pH, conductivity, osmolality, protein concentration, SEC, CEX, rCE, icIEF, subvisible, and visible particle characterization.
Analyze data generated from the above-listed activities, including statistical analysis using SAS, JMP, etc., and effectively communicate results
Serve as the primary point of contact and subject matter expert (SME) on complex capabilities and own business process
Write and own SOPs/methods/user guidance documents
Collaborate with program teams for successful implementation of studies
Maintain equipment procedures, study log books, scheduling, metrics, training, etc.
Participate in data management initiatives, such as integration of data from lab instruments with Electronic Lab Notebooks (ELN) to streamline and automate data collection
Troubleshoot malfunctioning equipment, work with Lab Operations, Asset Management, and vendors to repair
Author/review technical documents, such as technical protocols, technical assessments, and regulatory documents
Assist with and coordinate new equipment procurement and installation
Perform tasks related to safety and compliance initiatives in the lab, including resolution of observations
Lead inventory levels of commonly used lab supplies and chemicals
What we expect of you
We are all different, yet we all use our unique contributions to serve patients.
Master’s degree in Engineering, Chemistry, Biology, Pharmaceutical Sciences, Life Sciences, or related and 2 years of experience in the Biotec or pharmaceutical industry OR
Bachelor’s degree in Engineering, Chemistry, Biology, Pharmaceutical Sciences, Life Sciences, or related and 4 years of experience in the Biotec or pharmaceutical industry
Hands-on experience in designing and implementing automation and high throughput screening studies on liquid handling platforms (e.g. Tecan, Hamilton, Andrew, Unchained Labs, etc.)
Hands-on experience implementing typical protein characterization techniques, i.e. SEC-UHPLC or CEX-UHPLC, rCE, icIEF, protein concentration measurement via UV-Vis, viscosity, and density.
Familiarity and relevant knowledge of pharmaceutical/biotechnology process development, especially formulation development and Drug Product unit operations, e.g. UF/DF, filling, lyophilization
Some of the vast rewards of working here
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
Full support and career-development resources to expand your skills, enhance your expertise, and improve your potential along your career journey
A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.
Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Amgen requires all staff in the United States, Puerto Rico and Canada to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.