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Amgen Sr. Associate Scientist - Cardiometabolic Disorders (In Vivo) in South San Francisco, California


You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Sr. Associate Scientist - Cardiometabolic Disorders (In Vivo)


What you will do

Let’s do this. Let’s change the world. The Cardiometabolic Department at Amgen in South San Francisco is seeking a highly motivated Senior Associate Scientist to be part of a fast-paced, integrated and interactive research group developing therapeutics to treat metabolic diseases. The successful candidate must have strong in vivo pharmacology skills to lead and support rodent studies and be able to independently design, perform and analyze cell-based assays and ex vivo tissue analysis.

In this vital role you will join a multidisciplinary, cross-functional team, collaborate with research scientists with diverse expertise and contribute to multiple projects at both early and later stages of the Discovery pipeline. The science-based, patient-first environment at Amgen will allow the successful candidate to reach his/her full potential and apply his/her scientific expertise to benefit patients who need innovative medicines.

Position Responsibilities

  • Contribute, both independently and as part of a team, to in-life portions of in vivo studies, including detailed note taking during all stages of a study, performing all necessary techniques with precision (collect baseline measures, randomization, dosing, sample collection, necropsy), monitoring animal health and welfare, prepare for harvests, and support ex vivo tissue and serum analysis

  • Independently design, perform, optimize and analyze cell assays and ex vivo tissue analysis

  • Analyze and interpret data, communicate with manager and colleagues in written and oral formats, share results at team meetings

  • Be accountable for accurate, organized and timely record keeping

  • Show good scientific judgment at the experiment and project level

  • Demonstrate commitment to compliance and lab safety

  • Enjoy working in teams and be comfortable working independently with minimal daily oversight


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a scientist with these qualifications.

Basic Qualifications

Master’s degree and 3 years of scientific experience


Bachelor’s degree and 5 years of scientific experience

Preferred Qualifications

  • Industry background, familiarity with screening workflow processes

  • Highly self-motivated, proactive, able to prioritize tasks and maintain focus in a fast paced research environment

  • Adaptability/flexibility to effectively work independently and as part of an engaged and productive team to deliver results and advance programs

Will embrace supporting both high-throughput routine screening tasks and digging deep into biology questions

  • Must demonstrate a strong commitment to animal welfare and compliance including having a thorough knowledge of the regulations for an in vivo facility and remain aligned with IACUC regulations

  • Excellent written and verbal communication and interpersonal skills

  • Extensive experience leading and performing in-life research studies in rodents; experience in the following disease areas a plus: NAFLD, obesity, diabetes, inflammation, in vivo bioluminescence imaging

  • Proficient in basic bio-methodology techniques, anesthesia and physiological monitoring, compound dosing, and sample collection

  • Ability to independently design and perform both low-throughput and high-throughput cell line- and primary cell-based experiments, analyze and interpret results; develop stable expression cell lines, CRISPR Cas9 KI cell lines, etc.

  • Expertise in the following: RNA and Protein isolation, qPCR, WB, ELISA, colorimetric assays, both biochemical and immunofluorescence-based cell analysis

  • Skilled in computerized data acquisition, post-acquisition processing and data analysis using analytical & graphic software, and data summarization

  • Desire to learn new skills, take on new ideas, branch out into new territory, develop new models, and collaborate with researchers all over the Research organization.


Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.