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Amgen Senior Scientist - Immuno-Oncology Research in South San Francisco, California


You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Senior Scientist - Immuno-Oncology Research


What you will do

Let’s do this. Let’s change the world. Amgen Oncology Research is seeking a highly motivated scientist to join and lead discovery research projects in the Immuno-Oncology group. We are seeking a researcher who is enthusiastic about exploring new areas of research including novel targets & technologies, being an integral member of the discovery research team, collaborating with scientists in multi-functional areas at Amgen, and contributing to Amgen’s drug development pipeline. In this vital role you will enable the discovery, validation, and mechanistic understanding of novel cancer immunotherapies for the treatment of cancer.

Key Responsibilities:

  • Lead immuno-oncology discovery research projects (as a Biology Lead in Project Teams) and develop novel immuno-oncology therapeutics.

  • Independently design experimental strategy, execute laboratory-based experiments, analyze data, and communicate and present in team and departmental meetings.

  • Stay up to date with relevant literature and incorporate findings into program strategies as well as experimental design and implementation.

  • Publish experimental findings in top-tier journals and present at leading scientific conferences.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of immunology or oncology experience


Master’s degree and 5 years of immunology or oncology experience


Bachelor’s degree and 7 years of immunology or oncology experience

Preferred Qualifications:

  • Doctorate degree with postdoctoral training and research experience in the field of immunology or cancer biology.

  • Demonstrate expertise in immunology and/or cancer biology as evidenced with publications in high impact journals and/or patents.

  • Demonstrate independence and creative thinking in designing in vitro and in vivo biological studies, as well as ability to troubleshoot and solve complex problems.

  • Demonstrate technical expertise in the following areas: multi-color flow cytometry, primary immune cell culture, and genetic engineering (molecular biology).

  • Hands-on experience with mRNA-transfection-based assays and 3D complex cell-based assays for co-culture of tumor cells, T cells and myeloid cells is highly preferred.

  • Direct experience with downstream target validation by understanding oncogenic signaling pathways is a plus.

  • Direct experience with T cell-targeted therapy development (e.g. CAR-T, TCR-T, bispecific antibodies, or small molecules) is a plus.

  • Direct experience with various preclinical animal models of cancer, including design of efficacy/PD (pharmacodynamics) endpoints, and/or adoptive T cell transfer is a plus.

  • Strong interpersonal communication skills, both verbal and written.

  • Effectively prioritize and implement next steps with efficient time management.


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The annual base salary range for this opportunity in South San Francisco is $132,612 - $154,758.

In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

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Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.