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Amgen Senior Scientist, Cardiometabolic Disorders in South San Francisco, California


You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Senior Scientist, Cardiometabolic Disorders


What you will do

Let’s do this. Let’s change the world. In this vital role you will be part of an interactive and fast paced drug discovery research group within the Cardiometabolic Disorders Therapeutic Area. The successful candidate will be a highly motivated individual responsible for establishing and performing laboratory-based assays to develop a deeper understanding of the underlying disease biology for top cardiometabolic indications and screening of potential therapeutics.


  • Establish in vitro cell-based assays mimicking disease biology. Candidate must independently lead assay development, demonstrating strong scientific judgement at both experiment and project levels.

  • Investigate the underlying mechanisms of disease biology by analyzing insights gleaned from single cell sequencing data and other in vitro and in vivo studies.

  • Collaborate with teams across the organization to support the drug discovery pipeline.

  • Effectively interpret and communicate results through oral presentations.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Sr. Scientist with these qualifications.

Basic Qualifications:

Doctorate degree or

Master’s degree and 3 years of scientific experience or

Bachelor’s degree and 5 years of scientific experience

Preferred Qualifications:

  • Strong understanding of genetic pathways altered in prevalent diseases like heart failure, amyloidosis, liver disease, or chronic kidney diseases.

  • Postdoctoral training preferred.

  • Technical expertise: Flow cytometry, high content imaging, general molecular biology, biochemical, immunoblotting, immunocytochemistry, RT-qPCR, immunoprecipitation, and ELISA.

  • Experience in establishing rodent genetic models of chronic diseases is advantageous.

  • Industry experience in preclinical assay development is also a plus.


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.