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Amgen Principal Scientist - Translational Immunology in South San Francisco, California


If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Principal Scientist - Translational Immunology


What you will do

Let’s do this. Let’s change the world. The Amgen Translational Immunology and Safety Sciences group based in South San Francisco, CA, is seeking a Principal Scientist to independently investigate immune related safety assessment with in vitro approaches and provide immuno-toxicological evaluation strategy to support Inflammation pipeline projects.

In this vital role you will supervise lab scientists, collaborate closely with toxicologists, pathologists, and scientists within the organization, and with multi-functional teams, perform literature-based evaluation and in vitro assays for various pipeline projects and present the work to cross-functional teams.


  • The candidate should be able to independently initiate and drive projects, intellectually supervise junior lab members.

  • Contribute to the project development as well as perform cellular immunological techniques, including multi-color flow cytometry, ELISA, MSD and in vitro immune cell assays.

  • The candidate with experience in human 3D culture system is strongly preferred.

  • The candidate is expected to have extensive immunology training and strong cellular immunology and cell culture technical skills.

  • In addition, the candidate should have strong verbal and written communication skills, be highly motivated, creative and collaborative.

  • The candidate should have a track record of independent critical thinking and scientific achievement in the area of immunology.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek has these qualifications:

Basic Qualifications:

Doctorate degree PhD, PharmD or MD and 2 years of immunology experience.


Master’s degree and 5 years of Immunology experience.


Bachelor’s degree and 7 years of Immunology experience.

Preferred Qualifications:

  • Candidates with immuno-toxicology experience.


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.