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Amgen Principal Scientist- Cytometry Sciences in South San Francisco, California


If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Principal Scientist- Cytometry Sciences


What you will do

Let’s do this. Let’s change the world. In this vital role you will have the ability work in the capacity to lead imaging efforts that includes the additional ability to teach others & personally learn additional relevant skills as appropriate.

We are seeking a motivated Principal Scientist with a broad base of imaging experience and skills as applied to basic research that uses cell lines, human blood specimens or other relevant tissues.

This is team-oriented, laboratory-centered role in a dynamic core facility that also supports flow cytometry. The applicant will serve as a subject matter expert that works with minimal direction and will integrate both individual benchwork contributions along with team-centered activities. Guiding and training others to design and perform experiments is therefore an important component of this role.

  • Demonstrate a versatile imaging ability to support high content and confocal imaging campaigns that range from high throughput screening efforts to more intensive mechanism of action oriented studies.

  • Compile data using modern analytical tools that may require coding skills as a component of the analytical output.

  • Guide others how to use the facility as well as to hold personal accountability for prioritized projects.

  • Evaluate and implement new analytical paths that demonstrate artificial intelligence and machine learning to ensure that raw and analyzed data are secured within the larger Amgen data infrastructure.

  • Work in a biosafety level 2 plus laboratory environment, to maintain laboratory safety for everyone that accesses the laboratory to initiate and complete risk assessments for new activities in the laboratory as appropriate.

  • Flex into complementary platforms as appropriate, such as flow cytometry.

  • Assess new technologies & make purchase recommendations to management as appropriate.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Principal Scientist with these qualifications.

Basic Qualifications:

  • Doctorate degree (PhD) and 3 years of life science experience OR

  • Master’s degree and 6 years of life science experience OR

  • Bachelor’s degree and 8 years of life science experience

Preferred Qualifications:

  • Education in the life sciences; Prior experience working in a biopharmaceutical company.

  • A solid understanding of good documentation practices & scientific conduct as defined by standard operating procedures.

  • Working knowledge of instrumentation such as the Opera Phenix, Leica SP8, and/or Dragonfly etc., and analytical approaches that leverage Imaris, Cell Painting, Cellpose etc.

  • Ability to leverage varied AI/ML analytical platforms as they emerge into our industry & work in a team structure with data scientists in synergy.

  • A working knowledge of how to integrate imaging & flow cytometry efforts with adjacent single cell technologies (e.g., RNA seq, CRISPR screens, etc).


What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.