Amgen Principal Scientist - Clinical Biomarker Development in South San Francisco, California

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is developing our Translational Science focus with modern molecular and cellular science and pathology laboratories, designed to discover and develop valuable biomarkers in support of clinical programs.

Amgen R&D Medical Sciences/Translational Sciences is looking for a Principal Scientist dedicated to Clinical biomarker development. This position will primarily support Oncology biomarker discovery and development. The successful candidate is expected to work cross-functionally within Amgen and to interact closely with both the clinical and discovery research groups. The position will focus on the development and execution of clinical biomarker assays to inform biochemical coverage, pharmacodynamics, and patient selection markers to support the progression of Amgen's pipeline candidates from late preclinical development through all stages of clinical development. The role is responsible for designing experiments, drafting and implementing protocols, executing studies, organizing data, analyzing results, and drafting technical reports or tech transfer documents.

Will interface with oncology research and is expected to work in a highly matrixed environment and drive scientific and technical innovation collaboratively with other members of the group, as well as with Amgen research community.

Amgen employees adhere to all corporate and local guidelines and regulations related to compliance and health and safety.

Basic Qualifications:

Doctorate degree and 3 years scientific experience


Master's degree and 6 years of scientific experience


Bachelor's degree and 8 years scientific experience

Preferred Qualifications:

Knowledge and experience in oncology and/or immuno-oncology

Strong background in tumor biology and cancer genomics

Strong laboratory experience in preclinical biomarker discovery/validation and/or implementing biomarker assays in a clinical trial setting

Experience implementing a broad array of platforms and technologies to support a research program

Experience in assay development and qualification and analysis of clinical samples

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.