Amgen Associate Scientist - Translational Immunology in South San Francisco, California
The Translational Immunobiology laboratory within the Comparative Biology and Safety Sciences organization at Amgen is seeking a talented Associate Scientist to drive the development and execution of custom in vitro immunological bioassays.
Responsibilities include executing human and pre-clinical species-based functional cellular assays to support the understanding of target biology, target expression, candidate safety liability, pharmacodynamic biomarker development, bioactivity or immune mechanistic issue resolution. Will also interact and collaborate with interdisciplinary scientists in the Translational Sciences and Discovery Research organizations, such as toxicology, biologics, bioinformatics, proteomics, genome analysis unit, oncology, inflammation, cardiometabolic and neuroscience disease areas. Understand target biology, design and execute assays to understand mechanism of action and predict immune mechanistic safety liabilities.
Master's degree and 2 years of Scientific experience
Bachelor's degree and 4 years of Scientific experience
Bachelor's degree with 6+ years of scientific experience or Master's degree with 4+ years of scientific experience
Background in immunology, cancer immunobiology and/or cell biology
Demonstrated expertise in working with a variety of in vitro immune and/or hematopoietic cellular systems including mixed cell culture systems and working with primary cells
Demonstrated expertise in cellular functional endpoint measures, including cell surface phenotypic changes, proliferation, activation, phagocytosis, target cell killing, production of soluble factors
Proficiency with a variety of molecular and cellular biology techniques including, but not limited to, flow cytometry, mass cytometry, cellular transfection/transduction, PCR, ELISA, etc.
Ability to work independently in experimental planning, design, execution, optimization, data analysis, interpretation and communication
Ability to balance moving projects forward in the face of continuously evolving priorities and timelines while creating an environment of scientific curiosity promoting the exchange of ideas
Excels in skills related to time management, attention to detail and documentation
Comfort with working in a highly interactive, interdisciplinary and vibrant environment and a passion for teamwork
A Fortune 150 company operating in nearly 100 countries around the world, we invest in highly skilled, dedicated and collaborative individuals who are ready to contribute to our mission in meaningful ways and make a difference in the lives of our patients. That's why, as a member of our cross functional, cross discipline team, we provide you with valuable opportunities to broaden your experience and maximize your potential. Focused on the industry's most compelling scientific discoveries and housed within industry leading facilities within the heart of the world's leading biotechnology hub, our colleagues are growing our pipeline through groundbreaking innovations. We believe in rewarding those who do rewarding work and are committed to providing careers that can help turn the tide of serious, life interrupting illnesses.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.