Amgen Associate Scientist- (level 4) in Shanghai, China
Amgen is a leading global biotechnology company with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients in China, Amgen established a Research and Development facility in Shanghai. Amgen R&D Center Discovery Research group focus on G protein-coupled receptors (GPCRs), an important class of signaling molecules and potential drug targets.
Amgen Asia R&D (Shanghai) Center Pharmacology group is looking for a highly self-motivated Research Associate/Senior Research Associate/Associate Scientist to work on development and execution of in vivo and in vitro cell-based assay. The successful candidate should have a M.S. degree with relevant experience in biology, molecular biology or pharmacology.
Responsibilities will include, but are not limited to the following:
Develop and execute in vivo and ex vivo experiments to support different projects.
Generate knockout, knockdown or overexpression cell system for target validation.
Perform ex vivo procedure and analysis including isolation of DNA/RNA from tissue, qPCR, western blotting, FACS and immunofluorescence staining.
Analyze and report results to the company database and project teams.
Hands-on experience in animal handling, breeding, primary cell isolation and culture
Experience with molecular and cellular biology techniques including molecular cloning, vector construction, maintenance of mammalian cell cultures and primary cells, DNA/RNA/ protein detection assays (qPCR/WB/IHC), siRNA and CRISPR/Cas9 based gene-editing techniques
Experience with biochemical and cell-based assays
Familiar with cardiovascular biology and related animal models (preferred but not required)
Team player with good communication and presentation skills
Proven ability to multi-task, work independently, meet timelines and work accurately
M.S. degree with experience in biotech or pharmaceutical industry
Fluent in reading, writing and speaking in Chinese and English