Auto req 13954BR
Job Posting Title Scientist
Career Category Research
Employee Subgroup Salaried FT
Country (State/Region) United States - California
Location (City) Thousand Oaks
Amgen Job Description Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.
As an organization dedicated to improving the quality of life for people around the globe, Amgen fosters an inclusive environment of diverse, committed and highly accomplished people. People who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.
We are currently seeking a Scientist for our Clinical Immunology group.
This role will:
• Design and execute specific scientific experiments for development, validation and implementation of methods capable of detecting anti-drug neutralizing antibodies or for measurement of drug biological activity in clinical and nonclinical study samples
• Develop and implement new and novel protocols to address specific issues and/or troubleshoot and improve currently existing assays towards being more sensitive, transferable, and high-throughput
• Conduct data analysis and interpretation, and assesses impact of the data on the project
• Provide technical support and expertise to department operating groups when needed
• Represent the department on cross-functional project teams
• Provide scientific oversight to transfer of assays to CROs
• Assist senior-level Scientists in managing clinical and/or non-clinical programs
• Contribute as lead author on scientific documents such as journal publications, technical reports, etc.
Basic Qualifications Doctorate degree
OR
Master’s degree & 3 years of directly related experience
OR
Bachelor’s degree & 5 years of directly related experience
Preferred Qualifications A successful candidate in this role should:
• Post doc experience preferred
• Demonstrate innovation in cell signaling, in vitro assay design
• Be able to solve complex problems demonstrating a deep understanding in a scientific area of expertise.
• Demonstrate ability to drive scientific excellence and innovation.
• Knowledge of the drug development process
• Have the ability to effectively present scientific information both internally and externally to influence decisions and/or scientific practices
• Demonstrate knowledge of the IND/NDA process
• General knowledge of the field of Immunology, Oncology, Immunochemistry, or Cell Biology and pertinent immunologic assays.
• Experience in in vitro cell-based assays and related technologies, in-depth knowledge of signal transduction processes.
• Development, validation, transfer and implementation of assays detecting and characterizing antibodies to protein products in biological matrices and/or measuring drug activity.
• Development, validation, transfer and implementation of fluorescence-based assays in cell lines, animal model and/or human specimens in collaboration with analysts and scientists in a variety of clinical / therapeutic areas.
• Project Management as it pertains to oversight of vendors, assay transfers and implementation of outsourced assays.
• Ability to communicate complex ideas to audiences with varying degrees of knowledge
• Initiative
• Attention to detail
• Independence of thought demonstrated through hypothesis formulation, experimental design, interpretation and innovation
• Demonstrated critical thinking with an ability to integrate data and information to solve complex problems
• Ability to collaborate on a functional and/or cross-functional team as a leader and/or a member
• Ability to build and manage a team
