Auto req 13963BR
Job Posting Title Principal Scientist
Career Category Clinical Development
Employee Subgroup Salaried FT
Country (State/Region) United States - California
Location (City) Thousand Oaks
Amgen Job Description This is an exciting opportunity in the Early Development/ Molecular Sciences group at Amgen that could be situated in either the Seattle, WA or Thousand Oaks, CA campus for an individual to explore and apply pharmacodynamic and patient stratification biomarkers in the context of informing the decision-making process in drug development for cardiovascular therapeutics. The successful candidate will be responsible for leading and coordinating the biomarker effort for a portfolio of concurrent research and clinical projects. This responsibility would extend from efforts discovering and evaluating candidate biomarkers to overseeing the execution of biomarker assessments in clinical trials. The candidate will drive the implementation of biomarker strategy in clinical studies through close collaboration with discovery research, preclinical and early clinical development teams in the metabolism and general medicine areas. The candidate will also be responsible for organizing and contributing to the cross-functional and cross-site team interaction including meetings, reports and presentations.
Basic Qualifications • Doctorate degree & 5 years of scientific experience
OR
• Master’s degree & 12 years of scientific experience
OR
• Bachelor’s degree & 15 years of scientific experience
Preferred Qualifications •Ph.D in life sciences and 2+ years of post-doctoral experience and 4+ years of industry experience.
•Experience in the discovery and implementation of biomarkers within clinical studies for cardiovascular disease (e.g. lipid regulation, dyslipidemia, atherosclerosis).
•Strong desire to be part of the flexible and dynamic environment of early development, and be capable of supporting a broad portfolio of novel projects.
•A strong background in cardiovascular biology, with emphasis on the understanding of pathway interventions applied as therapeutics.
•Strong skills in critical thinking, laboratory experimentation and analysis, and understanding of the advantages and limitations of exploratory analyses in the clinical setting.
•Effective communication and interpersonal skills and the ability to work in a matrix environment are essential.
