[{"country_short": "CAN", "city": null, "description": "Auto req 15574BR\nJob Posting Title Co-op Student: Hybridoma Subcloning and ESN Generation\nCareer Category College Job\nEmployee Subgroup Co-Op FT Salaried\nCountry (State/Region) Canada\nLocation (City) Burnaby\nAmgen Job Description Amgen British Columbia Inc., one of several research facilities operated by Amgen Inc., specializes in the discovery and development of human therapeutic antibodies. The research center, located in Burnaby, became part of Amgen with Amgen\u2019s acquisition of Abgenix, Inc. in April 2006. It employs approximately 65 people, including research scientists and a small support staff. Amgen is headquartered in the United States and has more than 17,000 staff members worldwide. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science\u2019s promise by bringing novel medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people\u2019s lives.\n\nThis project involves the discovery of novel human therapeutics or diagnostics using XenoMax\u2122 and Hybridoma technology. These two technologies allow identification of single immune cells from a large population that produces very high affinity antigen specific monoclonal antibodies. Another key component of the company is the Xenomouse\u2122, which is a proprietary transgenic mouse capable of producing fully human antibodies. The marriage of these technologies allows us to produce human antibodies against targets that would normally be considered self\u201d.\n\nThe candidate will be working in the Cell Biology/Subcloning group, which is responsible for using a FACs ARIA single cell sorter to isolate hybridoma\u2019s of interest. Hybridoma\u2019s are then scaled up and used to generate ESN supernatant, which will contain antibody of interest for further assays. The candidate will be responsible for reagent generation, maintenance of both FACS Caliburs and Aria, use of FACsAria for single cell sorting, cell culture, cell banking and harvesting of supernatants. The candidate will also be involved with our Robotics liquid handling platforms to aid in the above work.\n\nAnticipated Achievements:\n\u2022 Learn and implement basic cell culture techniques such as sterile technique, splitting cells, optimizing growth conditions, cryovial preservation of mammalian cells, media preparation for various cell lines\n\u2022 Gain experience in both FACS Calibur and Aria systems as well as Robotics\n\u2022 Gain much valuable experience in time organization and multitasking.\n\u2022 Become proficient in background searches and internet research.\n\u2022 Independently carry out projects depending on needs of company\n\n\nAll candidates will be subject to the verification of current college enrollment as well as a Canadian criminal records check prior to employment.\n\nAmgen retains the right to add or change the duties of the position at any time.\nAs an EEO/AA M/F/V/D employer, Amgen values and encourages diversity in the workplace\nBasic Qualifications \u2022 Must be in the process of earning a Bachelors of Science degree in Chemistry, Molecular Biology, Biochemistry,  Biology/Microbiology, Life Sciences, Chemical Engineering, or related discipline.\n\u2022 Must be able to work for two consecutive four month terms with continued employment for the second term dependant on a positive performance review at the end of the first term.\n\u2022 Must be NSERC eligible\n.\n\nAmgen requires that all individuals applying for an internship or a co-op assignment at Amgen must meet the following criteria:\n\u2022 Must be 18 years or older\n\u2022 Must be a current full time student\n\u2022 Must have completed at least one full year of study\n\u2022 Must have not yet graduated\n\u2022 Must be in good academic standing within their majors and overall at their university\n\u2022 Must be enrolled in school the fall season following the potential internship or co-op assignment\n\u2022 Must not be employed at the time the internship starts\nPreferred Qualifications \u2022 Prefer students with previous lab experience.\n\u2022 Prior experience in tissue culture is desired, experience in immunology and immunofluorescence techniques would be preferred.\n\u2022 General knowledge of immunology & molecular biology would be an asset.\n\u2022 Excellent organizational skills and attention to detail.\n\u2022 Function effectively as part of a team.", "date_new": "2012-05-03 18:02:03", "url": "http://www.amgen.jobs/xml/28403685/job", "country": "Canada", "company": "Amgen", "title": "Co-op Student: Hybridoma Subcloning and ESN Generation", "reqid": "15574BR", "state": null, "state_short": null, "location": "Virtual, CAN", "uid": 28403685}, {"country_short": "CAN", "city": null, "description": "Auto req 15576BR\nJob Posting Title Co-op Student: Cell Based Screening & Assay Development\nCareer Category College Job\nEmployee Subgroup Co-Op FT Salaried\nCountry (State/Region) Canada\nLocation (City) Burnaby\nAmgen Job Description Amgen British Columbia, one of Burnaby\u2019s premier biotechnology companies, is focused on the development and commercialization of therapeutic antibody products targeting disease prevention and treatment. The company's antibody technology platform enables the rapid generation and selection of high affinity, fully human antibody product candidates to essentially any disease target appropriate for antibody therapy.\n\nWorking in partnership with our U.S. based parent company, Amgen Inc., Amgen British Columbia leverages its leading technology, flexible manufacturing capabilities and a network of partnerships for the discovery, development and manufacture of therapeutic antibodies for serious health conditions. For more information, please visit our website at www.amgen.com.\n\nJob Summary:\n\nThe student will be part of a high-energy, fast paced team responsible for cell screening and assay development in our antibody generation process. The team utilizes Flow Cytometry and FMAT as the screening platforms and also utilizes high capacity liquid handling robotics. In addition to becoming proficient in our screening platforms and process, the student is expected to maintain a variety of cell lines and is responsible for cell transfections. The student will have the opportunity to develop novel assays to assist in characterizing lead antibodies.\n\nEssential Functions:\n\n\u2022 Performs a variety of Cell-based assays:\n\u2022 assays used to characterize the immune response in immunized animals\n\u2022 high-throughput cell screens to identify antigen specific antibodies\n\u2022 functional assays to characterize antibodies for epitope specificity, ligand blocking and species reactivity\n\u2022 Gain strong working knowledge of Flow Cytometry, FMAT and ELISA\n\u2022 Critically evaluate data and present results to the team\n\u2022 Tissue culture and transfections\n\u2022 Optimize/develop assays\n\n\nAll candidates will be subject to the verification of current college enrollment as well as a Canadian criminal records check prior to employment.\n\nAmgen retains the right to add or change the duties of the position at any time.\nAs an EEO/AA M/F/V/D employer, Amgen values and encourages diversity in the workplace\nBasic Qualifications \u2022 Must be in the process of earning a Bachelors of Science degree in Chemistry, Molecular Biology, Biochemistry,  Biology/Microbiology, Life Sciences, Chemical Engineering, or related discipline.\n\u2022 Must be able to work for two consecutive four month terms with continued employment for the second term dependant on a positive performance review at the end of the first term.\n\u2022 Must be NSERC eligible.\n\nAmgen requires that all individuals applying for an internship or a co-op assignment at Amgen must meet the following criteria:\n\u2022 Must be 18 years or older\n\u2022 Must be a current full time student\n\u2022 Must have completed at least one full year of study\n\u2022 Must have not yet graduated\n\u2022 Must be in good academic standing within their majors and overall at their university\n\u2022 Must be enrolled in school the fall season following the potential internship or co-op assignment\n\u2022 Must not be employed at the time the internship starts\nPreferred Qualifications \u2022 Prefer students with previous lab experience.\n\u2022 General knowledge of immunology & molecular biology would be an asset.\n\u2022 Excellent organizational skills and attention to detail.\n\u2022 Function effectively as part of a team.", "date_new": "2012-05-03 18:01:15", "url": "http://www.amgen.jobs/xml/28403677/job", "country": "Canada", "company": "Amgen", "title": "Co-op Student: Cell Based Screening & Assay Development", "reqid": "15576BR", "state": null, "state_short": null, "location": "Virtual, CAN", "uid": 28403677}, {"country_short": "CAN", "city": null, "description": "Auto req 15575BR\nJob Posting Title Co-op Student: In Vivo\nCareer Category College Job\nEmployee Subgroup Co-Op FT Salaried\nCountry (State/Region) Canada\nLocation (City) Burnaby\nAmgen Job Description Amgen British Columbia, one of several research facilities operated by Amgen Inc., specializes in the discovery and development of human therapeutic antibodies. The research center, located in Burnaby, became part of Amgen with Amgen\u2019s acquisition of Abgenix, Inc. in April 2006. It employs approximately 50 people, including research scientists and a small support staff. Amgen is headquartered in the United States and has more than 17,000 staff members worldwide. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science\u2019s promise by bringing novel medicines from lab, to manufacturing plant, to patient. Amgen therapeutics has changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people\u2019s lives.\n\nJob Summary\n\nThe successful candidate will work as part of the Preclinical group at Amgen British Columbia Inc. The student will be responsible for performing a variety of in vivo and in vitro cell biology techniques used to evaluate potential cancer targets and oncology drug candidates. Experiments will be conducted in a semi-independent fashion under supervision. There are a variety of projects currently ongoing in the Preclinical group and these projects change frequently. The student will be involved in some or all of these projects as needed.\n\nEssential Functions\n\nThe job involves assisting researchers in all aspects of in vivo and in vitro studies. There will be some routine aseptic cell culture and flow cytometry. In addition, depending on current projects student may learn some or all of the following:\n\nIn vivo studies: study design, data collection, treatment formulation prep, animal handling, tumor measurement and data analysis.\n\nIn Vitro studies: ELISA, SDS-PAGE, Western Blots and cell-based assays evaluating cytokine release, T cell or NK cell activation, proliferation or apoptosis.\n\n\nAll candidates will be subject to the verification of current college enrollment as well as a Canadian criminal records check prior to employment.\n\nWe request that all applicants include a cover letter with their resume when they apply. Applicants without a cover letter may not be considered for the position.\n\nAmgen retains the right to add or change the duties of the position at any time.\nAs an EEO/AA M/F/V/D employer, Amgen values and encourages diversity in the workplace\nBasic Qualifications \u2022 Must be in the process of earning a Bachelors of Science degree in Chemistry, Molecular Biology, Biochemistry,  Biology/Microbiology, Life Sciences, Chemical Engineering, or related discipline.\n\u2022 Must be able to work for two consecutive four month terms with continued employment for the second term dependant on a positive performance review at the end of the first term.\n\u2022 Must be NSERC eligible\n.\n\nAmgen requires that all individuals applying for an internship or a co-op assignment at Amgen must meet the following criteria:\n\u2022 Must be 18 years or older\n\u2022 Must be a current full time student\n\u2022 Must have completed at least one full year of study\n\u2022 Must have not yet graduated\n\u2022 Must be in good academic standing within their majors and overall at their university\n\u2022 Must be enrolled in school the fall season following the potential internship or co-op assignment\n\u2022 Must not be employed at the time the internship starts\nPreferred Qualifications \u2022 Suitable for a first or second work term as all training will be provided.\n\u2022 General knowledge of In Vivo studies, immunology & molecular biology would be an asset.\n\u2022 High attention to detail and able to comply with written procedures.\n\u2022 Strong written and oral communications skills in English.\n\u2022 Excellent organizational skills.\n\u2022 Function effectively as part of a team.", "date_new": "2012-05-03 18:01:04", "url": "http://www.amgen.jobs/xml/28403671/job", "country": "Canada", "company": "Amgen", "title": "Co-op Student: In Vivo", "reqid": "15575BR", "state": null, "state_short": null, "location": "Virtual, CAN", "uid": 28403671}]