Amgen Jobshttp://www.amgen.jobs2012-05-26 15:00:19.061041CANNoneAuto req 15811BR Job Posting Title Senior Associate, Supply Chain Career Category Supply Chain Employee Subgroup Salaried FT Country (State/Region) Canada Location (City) Mississauga Amgen Job Description Position: Senior Associate, Supply Chain Reports to: Supply Chain Senior Manager Grade Level: 4 Starting: June 2012 Location: Mississauga, ON (Head Office) Internal applicants are required to have a discussion with their current manager regarding intent to apply. Job Description: General Accountability - Planning & scheduling of commercial goods in Canada in order to achieve seamless service to patients. Administer and manage local commercial inventories working together with our distribution group and 3rd party logistics providers. SAP Lead for item master inputs & metrics reporting. Strong collaboration with local & corporate groups in order to achieve these accountabilities. Specific Responsibilities - Work with Supply Chain Senior Manager to manage local forecast planning, product supply planning and inventory / scrap planning. Maintain every patient-every-time performance. - Prepare monthly product supply files with actual, LE, & budget data. Work with Finance partner on validating planning inputs within Global system. Liaise with Finance on implementing enhanced forecasting techniques to manage submission deadlines to Corporate. - Modeling demand variability: Perform regular and ad-hoc depletion simulations, aging analysis and scrap scenarios for existing products & new launches. - Performance metrics: Develop and manage performance dashboards to report on SKU Splits tracking, New Product Launches, Forecast Accuracy, & Inventory / Scrap value. - Work with distribution group in optimizing inventory plan of Canadian distribution centers. - Work with analytics group on forecast scenarios & reporting for commercial products. - Active participation in Consensus Forecast & Forecast accuracy meetings. - Active participation in Global Inventory meetings to support SAP master data accuracy initiatives. - ERP: Responsible for SAP item master inputs & validation to support existing products & new product launches. - APO: Responsible for monthly planning inputs in APO aligned with Corporate planning cycles. Basic Qualifications Selection Criteria: - 3 to 5 years supply chain experience (pharmaceutical industry preferred) - Bachelor’s degree – B.A. or B.Sc. - Experience in SAP (Plan to Stock module specifically), APO experience would be an asset or similar enterprise planning systems experience - Strong analytical & problem solving skills, Solutions mindset, strong attention to detail - Expertise in Microsoft office applications (Excel, Word, Powerpoint), Microsoft Project would be an asset - Strong interpersonal & written communications skills - High achiever with a keen interest in Supply Chain2012-05-24 19:02:47CanadaAmgenNone15811BRNoneVirtual, CAN28931861http://www.amgen.jobs/xml/28931861/jobCANNoneAuto req 15518BR Job Posting Title Scientist - Biologics Discovery Career Category Scientific Employee Subgroup Salaried FT Country (State/Region) Canada Location (City) Burnaby Amgen Job Description Amgen’s Therapeutic Discovery (TD) organization seeks an experienced and outstanding Scientist to support the Biologics Discovery efforts undertaken at Amgen British Columbia. Amgen’s research facility located in Burnaby, British Columbia, Canada is focussed on the use of XenoMouse technology for the generation and characterization of therapeutic antibody panels. The successful employee will be responsible for providing scientific leadership and participate in the strategic design of the screens used to select best-in-class therapeutic molecules, by leveraging experience in large molecule pharmacodynamics, pharmacokinetics and biophysical interactions. In addition, this scientist will develop and carry out biochemical characterization screens utilizing BiaCore, KinExA, ForteBio and other common platform screening technologies. A core component of this role will be the development of novel and innovative screening methods to interrogate properties of molecules which will aide the selection of the best drug candidate panels. The successful incumbent also will develop high throughput screening, binding assays and innovative platform technologies that enable the selection of best therapeutic drug panel. Other responsibilities will include working locally and cross-site with scientists within other functional areas of the Therapeutic Discovery department and the greater Discovery Research organization to develop therapeutic design goals and recommendations on the best strategy for identifying the molecule of interest. Basic Qualifications • Doctorate degree OR • Master’s degree & 6 years of scientific experience OR • Bachelor’s degree & 8 years of scientific experience Preferred Qualifications • Ph.D. degree, or equivalent, in biochemistry, analytical chemistry, biophysics, pharmaceutical sciences, chemistry, or related field with 3-5 years of postgraduate research experience • Large molecule drug development experience with an emphasis on pharmacokinetics and biophysical interactions. • Theoretical and practical understanding and experience in wet biochemistry, assay development and screening, and associated instrumentation with special skill sets in Biacore, ForteBio and KinExA • Experience with laboratory automation and information technology • Strong abilities in trouble-shooting, problem-solving, data review and interpretation, and multi-tasking • Excellent written and oral communication skills. • Enthusiasm for working in a fast-paced, multi-disciplinary, team-based environment2012-05-14 18:34:21CanadaAmgenNone15518BRNoneVirtual, CAN28674601http://www.amgen.jobs/xml/28674601/jobCANNoneAuto req 15700BR Job Posting Title Sr Associate Contract Management (Contract) Career Category Clinical Employee Subgroup Salaried FT Country (State/Region) Canada Location (City) Mississauga Amgen Job Description Position: Senior Associate Clinical Contracts & Budgets Reports to: Manager, Clinical Research Services Grade: 4 Starting:August 2012 (13-month maternity-leave contract) Location: Head Office, Mississauga Internal Candidates are required to have a discussion with their current manager regarding intent to apply. Job Purpose: To manage all site-related contracting and budget negotiations and to process and track related payments in a timely and efficient manner. Key Job Functions: 1. Negotiates contract with clinical trial site, responding to comments within defined parameters set (produced by Legal) and seeking legal input for issues outside parameters set 2. Leads the review of the budget template with local project manager for country feedback on FMV (Fair Market Value) and the Schedule A template 3. Negotiates site budget from the base budget and payment milestones using appropriate guidelines 4. Escalates contract/budget issues to Legal, Pricing, and/or local & global study manager as appropriate 5. Coordinates and participates in meetings with site/legal to resolve contract issues 6. Manages, executes and reconciles payments ensuring that spending is within approved contract budgets 7. Maintains contract and payment data tracking in appropriate databases and financial systems 8. Manage internal stakeholder needs and expectations through regular communication regarding progress/status of pending contract and payment requests. 9. Actively contributes to results-oriented global and local departmental goals 10. Identifies opportunities and best practices with local and regional partners that will contribute to overall operational effectiveness Basic Qualifications Qualifications/Experience • Bachelor’s degree in a science or business field • 3-5 years or more related experience in finance administration, project management, contracting or other relevant work experience in life sciences or medically related field • Work experience in clinical research obtained working on clinical trials in a biotech, pharmaceutical or CRO is preferred. Competencies • Ability to work independently with little supervision as well as in a team environment • Strong Negotiation skills • Strong analytical and presentation skills • Excellent written and oral communication skills • Attention to detail • Persistent, tactful and persuasive • Proficiency with computer/database systems • Strong organizational skills with the ability to manage multiple priorities2012-05-11 18:20:30CanadaAmgenNone15700BRNoneVirtual, CAN28633380http://www.amgen.jobs/xml/28633380/jobCANNoneAuto req 15574BR Job Posting Title Co-op Student: Hybridoma Subcloning and ESN Generation Career Category College Job Employee Subgroup Co-Op FT Salaried Country (State/Region) Canada Location (City) Burnaby Amgen Job Description Amgen British Columbia Inc., one of several research facilities operated by Amgen Inc., specializes in the discovery and development of human therapeutic antibodies. The research center, located in Burnaby, became part of Amgen with Amgen’s acquisition of Abgenix, Inc. in April 2006. It employs approximately 65 people, including research scientists and a small support staff. Amgen is headquartered in the United States and has more than 17,000 staff members worldwide. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing novel medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives. This project involves the discovery of novel human therapeutics or diagnostics using XenoMax™ and Hybridoma technology. These two technologies allow identification of single immune cells from a large population that produces very high affinity antigen specific monoclonal antibodies. Another key component of the company is the Xenomouse™, which is a proprietary transgenic mouse capable of producing fully human antibodies. The marriage of these technologies allows us to produce human antibodies against targets that would normally be considered self”. The candidate will be working in the Cell Biology/Subcloning group, which is responsible for using a FACs ARIA single cell sorter to isolate hybridoma’s of interest. Hybridoma’s are then scaled up and used to generate ESN supernatant, which will contain antibody of interest for further assays. The candidate will be responsible for reagent generation, maintenance of both FACS Caliburs and Aria, use of FACsAria for single cell sorting, cell culture, cell banking and harvesting of supernatants. The candidate will also be involved with our Robotics liquid handling platforms to aid in the above work. Anticipated Achievements: • Learn and implement basic cell culture techniques such as sterile technique, splitting cells, optimizing growth conditions, cryovial preservation of mammalian cells, media preparation for various cell lines • Gain experience in both FACS Calibur and Aria systems as well as Robotics • Gain much valuable experience in time organization and multitasking. • Become proficient in background searches and internet research. • Independently carry out projects depending on needs of company All candidates will be subject to the verification of current college enrollment as well as a Canadian criminal records check prior to employment. Amgen retains the right to add or change the duties of the position at any time. As an EEO/AA M/F/V/D employer, Amgen values and encourages diversity in the workplace Basic Qualifications • Must be in the process of earning a Bachelors of Science degree in Chemistry, Molecular Biology, Biochemistry, Biology/Microbiology, Life Sciences, Chemical Engineering, or related discipline. • Must be able to work for two consecutive four month terms with continued employment for the second term dependant on a positive performance review at the end of the first term. • Must be NSERC eligible . Amgen requires that all individuals applying for an internship or a co-op assignment at Amgen must meet the following criteria: • Must be 18 years or older • Must be a current full time student • Must have completed at least one full year of study • Must have not yet graduated • Must be in good academic standing within their majors and overall at their university • Must be enrolled in school the fall season following the potential internship or co-op assignment • Must not be employed at the time the internship starts Preferred Qualifications • Prefer students with previous lab experience. • Prior experience in tissue culture is desired, experience in immunology and immunofluorescence techniques would be preferred. • General knowledge of immunology & molecular biology would be an asset. • Excellent organizational skills and attention to detail. • Function effectively as part of a team.2012-05-03 18:02:03CanadaAmgenNone15574BRNoneVirtual, CAN28403685http://www.amgen.jobs/xml/28403685/jobCANNoneAuto req 15576BR Job Posting Title Co-op Student: Cell Based Screening & Assay Development Career Category College Job Employee Subgroup Co-Op FT Salaried Country (State/Region) Canada Location (City) Burnaby Amgen Job Description Amgen British Columbia, one of Burnaby’s premier biotechnology companies, is focused on the development and commercialization of therapeutic antibody products targeting disease prevention and treatment. The company's antibody technology platform enables the rapid generation and selection of high affinity, fully human antibody product candidates to essentially any disease target appropriate for antibody therapy. Working in partnership with our U.S. based parent company, Amgen Inc., Amgen British Columbia leverages its leading technology, flexible manufacturing capabilities and a network of partnerships for the discovery, development and manufacture of therapeutic antibodies for serious health conditions. For more information, please visit our website at www.amgen.com. Job Summary: The student will be part of a high-energy, fast paced team responsible for cell screening and assay development in our antibody generation process. The team utilizes Flow Cytometry and FMAT as the screening platforms and also utilizes high capacity liquid handling robotics. In addition to becoming proficient in our screening platforms and process, the student is expected to maintain a variety of cell lines and is responsible for cell transfections. The student will have the opportunity to develop novel assays to assist in characterizing lead antibodies. Essential Functions: • Performs a variety of Cell-based assays: • assays used to characterize the immune response in immunized animals • high-throughput cell screens to identify antigen specific antibodies • functional assays to characterize antibodies for epitope specificity, ligand blocking and species reactivity • Gain strong working knowledge of Flow Cytometry, FMAT and ELISA • Critically evaluate data and present results to the team • Tissue culture and transfections • Optimize/develop assays All candidates will be subject to the verification of current college enrollment as well as a Canadian criminal records check prior to employment. Amgen retains the right to add or change the duties of the position at any time. As an EEO/AA M/F/V/D employer, Amgen values and encourages diversity in the workplace Basic Qualifications • Must be in the process of earning a Bachelors of Science degree in Chemistry, Molecular Biology, Biochemistry, Biology/Microbiology, Life Sciences, Chemical Engineering, or related discipline. • Must be able to work for two consecutive four month terms with continued employment for the second term dependant on a positive performance review at the end of the first term. • Must be NSERC eligible. Amgen requires that all individuals applying for an internship or a co-op assignment at Amgen must meet the following criteria: • Must be 18 years or older • Must be a current full time student • Must have completed at least one full year of study • Must have not yet graduated • Must be in good academic standing within their majors and overall at their university • Must be enrolled in school the fall season following the potential internship or co-op assignment • Must not be employed at the time the internship starts Preferred Qualifications • Prefer students with previous lab experience. • General knowledge of immunology & molecular biology would be an asset. • Excellent organizational skills and attention to detail. • Function effectively as part of a team.2012-05-03 18:01:15CanadaAmgenNone15576BRNoneVirtual, CAN28403677http://www.amgen.jobs/xml/28403677/jobCANNoneAuto req 15575BR Job Posting Title Co-op Student: In Vivo Career Category College Job Employee Subgroup Co-Op FT Salaried Country (State/Region) Canada Location (City) Burnaby Amgen Job Description Amgen British Columbia, one of several research facilities operated by Amgen Inc., specializes in the discovery and development of human therapeutic antibodies. The research center, located in Burnaby, became part of Amgen with Amgen’s acquisition of Abgenix, Inc. in April 2006. It employs approximately 50 people, including research scientists and a small support staff. Amgen is headquartered in the United States and has more than 17,000 staff members worldwide. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing novel medicines from lab, to manufacturing plant, to patient. Amgen therapeutics has changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives. Job Summary The successful candidate will work as part of the Preclinical group at Amgen British Columbia Inc. The student will be responsible for performing a variety of in vivo and in vitro cell biology techniques used to evaluate potential cancer targets and oncology drug candidates. Experiments will be conducted in a semi-independent fashion under supervision. There are a variety of projects currently ongoing in the Preclinical group and these projects change frequently. The student will be involved in some or all of these projects as needed. Essential Functions The job involves assisting researchers in all aspects of in vivo and in vitro studies. There will be some routine aseptic cell culture and flow cytometry. In addition, depending on current projects student may learn some or all of the following: In vivo studies: study design, data collection, treatment formulation prep, animal handling, tumor measurement and data analysis. In Vitro studies: ELISA, SDS-PAGE, Western Blots and cell-based assays evaluating cytokine release, T cell or NK cell activation, proliferation or apoptosis. All candidates will be subject to the verification of current college enrollment as well as a Canadian criminal records check prior to employment. We request that all applicants include a cover letter with their resume when they apply. Applicants without a cover letter may not be considered for the position. Amgen retains the right to add or change the duties of the position at any time. As an EEO/AA M/F/V/D employer, Amgen values and encourages diversity in the workplace Basic Qualifications • Must be in the process of earning a Bachelors of Science degree in Chemistry, Molecular Biology, Biochemistry, Biology/Microbiology, Life Sciences, Chemical Engineering, or related discipline. • Must be able to work for two consecutive four month terms with continued employment for the second term dependant on a positive performance review at the end of the first term. • Must be NSERC eligible . Amgen requires that all individuals applying for an internship or a co-op assignment at Amgen must meet the following criteria: • Must be 18 years or older • Must be a current full time student • Must have completed at least one full year of study • Must have not yet graduated • Must be in good academic standing within their majors and overall at their university • Must be enrolled in school the fall season following the potential internship or co-op assignment • Must not be employed at the time the internship starts Preferred Qualifications • Suitable for a first or second work term as all training will be provided. • General knowledge of In Vivo studies, immunology & molecular biology would be an asset. • High attention to detail and able to comply with written procedures. • Strong written and oral communications skills in English. • Excellent organizational skills. • Function effectively as part of a team.2012-05-03 18:01:04CanadaAmgenNone15575BRNoneVirtual, CAN28403671http://www.amgen.jobs/xml/28403671/job