Amgen Scientist - Protein Chemistry in Cambridge, Massachusetts
Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is hiring in the Department of Protein Technologies, Biologics, at our Research and Development facility in Cambridge, MA (AMA).
We are looking for a highly motivated and talented biochemist to join the AMA Protein Technologies group. This laboratory provides comprehensive molecular biology and biochemistry support for the early stage pipeline of projects including both protein and small molecule therapeutics. The successful candidate will have the opportunity to contribute directly to the exciting drug discovery process on a wide variety of important biological systems.
The candidate's responsibilities include (but not limited to) protein purification, biochemical characterization, and protein expression in various hosts. The successful candidate will work in teams to develop, implement, and perform protein purification protocols for a variety of protein classes, including integral membrane proteins. Additional responsibilities include planning detailed procedures for research projects including timelines, methodological approaches, expected results and necessary resources; analyzing and interpreting scientific data and results; providing regular updates, documentation, and/or communication on project results; and supporting the generation of publications, patents, or regulatory submissions.
The scientist will work closely with other molecular biologists and protein biochemists in the Protein Technologies group as well as colleagues in Therapeutic Discovery and therapeutic areas. He/she should demonstrate excellent verbal and written communication skills.
*Doctorate degree or Doctorate Degree completed by August 2017
*Master's degree and 4 years of scientific experience
*Bachelor's degree and 6 years of scientific experience
*PhD with focus on Biochemistry or Molecular Biology
*Proven track record of academic accomplishments (i.e., peer-reviewed publications and/or patents)
*Knowledge of state-of-the-art protein biochemistry techniques.
*Proficient with AKTA chromatography hardware and software.
*Proficient with a range of chromatography methods (affinity, ion-exchange, HIC, gel-filtration).
*Experience with mammalian, microbial or insect expression
*Experience in the expression/purification of membrane proteins is a plus.
*Excellent communication skills (both written and oral) and the ability to work well in teams
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.